Later on, witnessed the introduction of Thiopentone Sodium after clinical trials by Lundy in 1934.
It was first used in human beings on March 8, 1934, by Dr. Ralph M. Waters (It was rumoured to have been overused at Pearl Harbour and responsible for many deaths. This is now known to be an exaggeration)
It is a credit to their ingenuity that the substance is still in common use today.
Cyclopropane was discovered in 1881 by August Freund. Cyclopropane had no commercial application until Henderson and Lucas discovered its anaesthetic properties in 1929; industrial production had begun by 1936. 215
Cyclopropane and other drugs gave more control to the anaesthetist.
In 1942 Curare or Tubocurarine was used by the Canadian Anaesthetist, Harold Griffiths. This particular substance was first mentioned by Peter Angherius (1516) It was 80 years later that Sir Walter Raleigh made mention of this poison.
In the 1940s, IPPV was being used more frequently because of the introduction of this drug Curare.
This was made by the South American Indians from ingredients taken from the forest and used by them to tip their arrows for both the blowpipe and the bow. 216
It was used to capture monkeys and other wildlife and also as a self-defence weapon.